The COVID‐19 pandemic changes citizens' visual aesthetic perceptions and attitudes toward restored landscape in the karst area in China

Landscape change caused by ecological restoration projects in the karst rocky desertification area of southwestern China has presented ecological benefits, yet the visual aesthetic perception of the restored landscape has received less attention. Meanwhile, given the unpredictable worldwide health emergency caused by the COVID‐19 pandemic, it inspired us to be concerned about will citizens' aesthetic perceptions and attitudes to the change of restored landscape from pre‐COVID‐19 to during the outbreak of the COVID‐19 pandemic. Organizing an online survey, we explored citizens' visual aesthetic perceptions and attitudes to natural restored landscape (NRL) and managed restored landscape (MRL) on 757 citizens in Shilin Geopark (in Kunming, China), as well as how citizens' sociocultural backgrounds influence visual aesthetic preference. The results indicated that before the COVID‐19 pandemic, the professionals preferred NRL, while the nonprofessionals presented a higher preference for MRL. However, during the COVID‐19 pandemic, both two groups showed a higher preference for NRL, which implied that the experience of lockdown during the COVID‐19 pandemic might awaken most citizens' preference for the NRL. Among different kinds of restored plant communities, the landscape dominated by shrubs was the most popular. Furthermore, gender, age, career type, education, region, and citizens' visit frequency were significantly correlated with visual aesthetic perceptions before the COVID‐19 pandemic. During the COVID‐19 pandemic, professional background, gender, and age did not show significant impacts on visual aesthetic perceptions anymore. These results highlight the necessity of understanding visual aesthetic perceptions in different sociodemographic groups to encourage natural succession and create a nature‐based restored landscape in the karst area. [ FROM AUTHOR] Copyright of Restoration Ecology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

The

Landscape change caused by ecological restoration projects in the karst rocky desertification area of southwestern China has presented ecological benefits, yet the visual aesthetic perception of the restored landscape has received less attention. Meanwhile, given the unpredictable worldwide health emergency caused by the COVID-19 pandemic, it inspired us to be concerned about will citizens' aesthetic perceptions and attitudes to the change of restored landscape from pre-COVID-19 to during the outbreak of the COVID-19 pandemic. Organizing an online survey, we explored citizens' visual aesthetic perceptions and attitudes to natural restored landscape (NRL) and managed restored landscape (MRL) on 757 citizens in Shilin Geopark (in Kunming, China), as well as how citizens' sociocultural backgrounds influence visual aesthetic preference. The results indicated that before the COVID-19 pandemic, the professionals preferred NRL, while the nonprofessionals presented a higher preference for MRL. However, during the COVID-19 pandemic, both two groups showed a higher preference for NRL, which implied that the experience of lockdown during the COVID-19 pandemic might awaken most citizens' preference for the NRL. Among different kinds of restored plant communities, the landscape dominated by shrubs was the most popular. Furthermore, gender, age, career type, education, region, and citizens' visit frequency were significantly correlated with visual aesthetic perceptions before the COVID-19 pandemic. During the COVID-19 pandemic, professional background, gender, and age did not show significant impacts on visual aesthetic perceptions anymore. These results highlight the necessity of understanding visual aesthetic perceptions in different sociodemographic groups to encourage natural succession and create a nature-based restored landscape in the karst area.

The COVID‐19 pandemic changes citizens' visual aesthetic perceptions and attitudes toward restored landscape in the karst area in China

Landscape change caused by ecological restoration projects in the karst rocky desertification area of southwestern China has presented ecological benefits, yet the visual aesthetic perception of the restored landscape has received less attention. Meanwhile, given the unpredictable worldwide health emergency caused by the COVID‐19 pandemic, it inspired us to be concerned about will citizens' aesthetic perceptions and attitudes to the change of restored landscape from pre‐COVID‐19 to during the outbreak of the COVID‐19 pandemic. Organizing an online survey, we explored citizens' visual aesthetic perceptions and attitudes to natural restored landscape (NRL) and managed restored landscape (MRL) on 757 citizens in Shilin Geopark (in Kunming, China), as well as how citizens' sociocultural backgrounds influence visual aesthetic preference. The results indicated that before the COVID‐19 pandemic, the professionals preferred NRL, while the nonprofessionals presented a higher preference for MRL. However, during the COVID‐19 pandemic, both two groups showed a higher preference for NRL, which implied that the experience of lockdown during the COVID‐19 pandemic might awaken most citizens' preference for the NRL. Among different kinds of restored plant communities, the landscape dominated by shrubs was the most popular. Furthermore, gender, age, career type, education, region, and citizens' visit frequency were significantly correlated with visual aesthetic perceptions before the COVID‐19 pandemic. During the COVID‐19 pandemic, professional background, gender, and age did not show significant impacts on visual aesthetic perceptions anymore. These results highlight the necessity of understanding visual aesthetic perceptions in different sociodemographic groups to encourage natural succession and create a nature‐based restored landscape in the karst area. [ FROM AUTHOR]

Artesunate: A review of its therapeutic insights in respiratory diseases.

BACKGROUND: Artesunate, as a semi-synthetic artemisinin derivative of sesquiterpene lactone, is widely used in clinical antimalarial treatment due to its endoperoxide group. Recent studies have found that artesunate may have multiple pharmacological effects, indicating its significant therapeutic potential in multiple respiratory diseases. PURPOSE: This review aims to summarize proven and potential therapeutic effects of artesunate in common respiratory disorders. STUDY DESIGN: This review summarizes the pharmacological properties of artesunate and then interprets the function of artesunate in various respiratory diseases in detail, such as bronchial asthma, chronic obstructive pulmonary disease, lung injury, lung cancer, pulmonary fibrosis, coronavirus disease 2019, etc., on different target cells and receptors according to completed and ongoing in silico, in vitro, and in vivo studies (including clinical trials). METHODS: Literature was searched in electronic databases, including Pubmed, Web of Science and CNKI with the primary keywords of 'artesunate', 'pharmacology', 'pharmacokinetics', 'respiratory disorders', 'lung', 'pulmonary', and secondary search terms of 'Artemisia annua L.', 'artemisinin', 'asthma', 'chronic obstructive lung disease', 'lung injury', 'lung cancer', 'pulmonary fibrosis', 'COVID-19' and 'virus' in English and Chinese. All experiments were included. Reviews and irrelevant studies to the therapeutic effects of artesunate on respiratory diseases were excluded. Information was sort out according to study design, subject, intervention, and outcome. RESULTS: Artesunate is promising to treat multiple common respiratory disorders via various mechanisms, such as anti-inflammation, anti-oxidative stress, anti-hyperresponsiveness, anti-proliferation, airway remodeling reverse, induction of cell death, cell cycle arrest, etc. CONCLUSION: Artesunate has great potential to treat various respiratory diseases.

COVID-19 mortality and exposure to airborne PM2.5: A lag time correlation.

COVID-19 has escalated into one of the most serious crises in the 21st Century. Given the rapid spread of SARS-CoV-2 and its high mortality rate, here we investigate the impact and relationship of airborne PM2.5 to COVID-19 mortality. Previous studies have indicated that PM2.5 has a positive relationship with the spread of COVID-19. To gain insights into the delayed effect of PM2.5 concentration (µgm-3) on mortality, we focused on the role of PM2.5 in Wuhan City in China and COVID-19 during the period December 27, 2019 to April 7, 2020. We also considered the possible impact of various meteorological factors such as temperature, precipitation, wind speed, atmospheric pressure and precipitation on pollutant levels. The results from the Pearson's correlation coefficient analyses reveal that the population exposed to higher levels of PM2.5 pollution are susceptible to COVID-19 mortality with a lag time of >18 days. By establishing a generalized additive model, the delayed effect of PM2.5 on the death toll of COVID-19 was verified. A negative correction was identified between temperature and number of COVID-19 deaths, whereas atmospheric pressure exhibits a positive correlation with deaths, both with a significant lag effect. The results from our study suggest that these epidemiological relationships may contribute to the understanding of the COVID-19 pandemic and provide insights for public health strategies.

The Influence of Corticosteroids, Immunosuppressants and Biologics on Patients With Inflammatory Bowel Diseases, Psoriasis and Rheumatic Diseases in the Era of COVID-19: A Review of Current Evidence.

Patients with inflammatory bowel disease, psoriasis or other rheumatic diseases treated with corticosteroids, immunomodulators and biologics might face additional risk during COVID-19 epidemic due to their immunocompromised status. However, there was still no unanimous opinion on the use of these therapy during COVID-19 epidemic. Current studies suggested that systemic corticosteroids might increase the risk of hospitalization, as well as risks of ventilation, ICU, and death among patients with immune-mediated inflammatory diseases. Anti-TNF agent was associated with lower rate of hospitalization, as well as lower risks of ventilation, ICU, and death. No significant changes in rates of hospitalization, ventilation, ICU and mortality were observed in patients treated with immunomodulators or biologics apart from anti-TNF agents. The underlying mechanism of these results might be related to pathway of antiviral immune response and cytokine storm induced by SARS-COV-2 infection. Decision on the use of corticosteroids, immunomodulators and biologics should be made after weighing the benefits and potential risks based on individual patients.

The role of airborne particles and environmental considerations in the transmission of SARS-CoV-2

Corona Virus Disease 2019 (COVID-19) caused by the novel coronavirus, results in an acute respiratory condition coronavirus 2 (SARS-CoV-2) and is highly infectious. The recent spread of this virus has caused a global pandemic. Currently, the transmission routes of SARS-CoV-2 are being established, especially the role of environmental transmission. Here we review the environmental transmission routes and persistence of SARS-CoV-2. Recent studies have established that the transmission of this virus can occur, amongst others, in the air, water, soil, cold-chain, biota, and surface contact. It has also been found that the survival potential of the SARS-CoV-2 virus is dependent on different environmental conditions and pollution. Potentially important pathways include aerosol and fecal matter. Particulate matter may also be a carrier for SARS-CoV-2. Since microscopic particles can be easily absorbed by humans, more attention must be focused on the dissemination of these particles. These considerations are required to evolve a theoretical platform for epidemic control and to minimize the global threat from future epidemics.

Impact of reduced anthropogenic emissions during COVID-19 on air quality in India

To mitigate the impacts of the pandemic of coronavirus disease 2019 (COVID-19), the Indian government implemented lockdown measures on 24 March 2020, which prohibited unnecessary anthropogenic activities, thus leading to a significant reduction in emissions. To investigate the impacts of this lockdown measure on air quality in India, we used the Community Multi-Scale Air Quality (CMAQ) model to estimate the changes of key air pollutants. From pre-lockdown to lockdown periods, improved air quality is observed in India, indicated by the lower key pollutant levels such as PM2.5 (-26 %), maximum daily 8 h average ozone (MDA8 O3) (-11 %), NO2 (-50 %), and SO2 (-14 %). In addition, changes in these pollutants show distinct spatial variations with the more important decrease in northern and western India. During the lockdown, our results illustrate that such emission reductions play a positive role in the improvement of air quality. Significant reductions of PM2.5 concentration and its major components are predicted, especially for secondary inorganic aerosols that are up to 92 %, 57 %, and 79 % for nitrate (NO3-), sulfate (SO42-), and ammonium (NH4+), respectively. On average, the MDA8 O3 also decreases 15 % during the lockdown period although it increases slightly in some VOC-limited urban locations, which is mainly due to the more significant reduction of NOx than VOCs. More aggressive and localized emission control strategies should be implemented in India to mitigate air pollution in the future.

Effect of restricted emissions during COVID-19 on air quality in India.

The effectiveness and cost are always top factors for policy-makers to decide control measures and most measures had no pre-test before implementation. Due to the COVID-19 pandemic, human activities are largely restricted in many regions in India since mid-March of 2020, and it is a progressing experiment to testify effectiveness of restricted emissions. In this study, concentrations of six criteria pollutants, PM10, PM2.5, CO, NO2, ozone and SO2 during March 16th to April 14th from 2017 to 2020 in 22 cities covering different regions of India were analysed. Overall, around 43, 31, 10, and 18% decreases in PM2.5, PM10, CO, and NO2 in India were observed during lockdown period compared to previous years. While, there were 17% increase in O3 and negligible changes in SO2. The air quality index (AQI) reduced by 44, 33, 29, 15 and 32% in north, south, east, central and western India, respectively. Correlation between cities especially in northern and eastern regions improved in 2020 compared to previous years, indicating more significant regional transport than previous years. The mean excessive risks of PM reduced by ~52% nationwide due to restricted activities in lockdown period. To eliminate the effects of possible favourable meteorology, the WRF-AERMOD model system was also applied in Delhi-NCR with actual meteorology during the lockdown period and an un-favourable event in early November of 2019 and results show that predicted PM2.5 could increase by only 33% in unfavourable meteorology. This study gives confidence to the regulatory bodies that even during unfavourable meteorology, a significant improvement in air quality could be expected if strict execution of air quality control plans is implemented.